Grasp allows you to make some decent trades in lane especially in melee matchups. In a ranged match up, you may want aftershock instead. Bone plating is a very good all purpose survivability rune and is a must for the 2nd row. All of the runes in the 3rd row are alright on ornn. If against poke champions like teemo, take second wind. If you have a sage laning phase, take conditioning for the extra resists. Otherwise, take chrisalis. Revitalize is the best option for the last row as it improve your already amazing w shield and potion regeneration. You can take overgrowth in safe matchups, but revitalize is generally better. For inspiration, the combination of biscuit, corrupting potion, and time warp tonic make you very hard to push out of lane. On a tank that can struggle in the early game, this is amazing.